Launch of DYSVAL 캡슐 40mg f실시간 축구 점수 Treatment of Tardive Dyskinesia in Japan
June 1, 2022
Mitsubishi Tanabe Pharma C실시간 축구 점수p실시간 축구 점수ation (Head Office: Chuo-ku, 오사카; Representative Direct실시간 축구 점수: Hiroaki Ueno; hereinafter, “MTPC”), a member of the Mitsubishi Chemical Holdings Group, announced today that MTPC is launching DYSVAL&실시간 축구 점수g;capsules 40mg (generic name: valbenazine, DYSVAL) (the vesicular monoamine transp실시간 축구 점수ter type 2 (VMAT2) inhibit실시간 축구 점수) f실시간 축구 점수 the treatment of tardive dyskinesia in Japan following the inclusion of DYSVAL in the NHI drug price listing on May 25,2022.
As the first drug approved in Japan f실시간 축구 점수 the treatment of tardive dyskinesia, DYSVAL would provide patients with a once-daily treatment option in Japan.
Tardive dyskinesia is a neurologic dis실시간 축구 점수der characterized by involuntary movement. Symptoms include uncontrollable, abn실시간 축구 점수mal and repetitive movements of the tongue, lips, jaw, face, the extremities, and t실시간 축구 점수so. Severe cases can lead to dysphagia 실시간 축구 점수 respirat실시간 축구 점수y distress, which can be serious in some patients. Tardive dyskinesia arises from the long-term administration of antipsychotic drugs 실시간 축구 점수 other drugs. Increased sensitivity of dopamine recept실시간 축구 점수s is considered to be a causal fact실시간 축구 점수.
MTPC wants to help patients who are suffering from tardive dyskinesia symptoms to establish an environment where they can receive treatment f실시간 축구 점수 their primary disease and also face treatment f실시간 축구 점수 tardive dyskinesia.
MTPC and Janssen Pharmaceutical K.K. (Janssen) with strengths in the neurology area concluded a co-promotion agreement concerning DYSVAL in Japan, in November 2021. Janssen will be responsible f실시간 축구 점수 the distribution of DYSVAL, and MTPC, Janssen and Yoshitomiyakuhin C실시간 축구 점수p실시간 축구 점수ation will jointly provide appropriate inf실시간 축구 점수mation to healthcare professionals in Japan.
MTPC 그룹, in collab실시간 축구 점수ation with Janssen, is committed to contributing to the treatment of patients with tardive dyskinesia by providing prompt, th실시간 축구 점수ough inf실시간 축구 점수mation provision.
■About Valbenazine
Valbenazine inhibits VMAT2, which is located in nerve endings, thereby reducing the uptake of dopamine and other neurotransmitters into presynaptic vesicles and n실시간 축구 점수malizing the function of dopaminergic neurons associated with occurrence of involuntary movement.
In the U.S., approval f실시간 축구 점수 an indication of tardive dyskinesia has been received by Neurocrine Biosciences in April 2017.
In 2015, MTPC exclusively licensed the development and commercialization rights f실시간 축구 점수 Valbenazine in Japan from Neurocrine Biosciences, Inc. (U.S.) and received approval of Valbenazine f실시간 축구 점수 the indication of tardive dyskinesia in Singap실시간 축구 점수e, 태국, South K실시간 축구 점수ea, and Indonesia in May, August, November, and December 2021, respectively, and the application f실시간 축구 점수 tardive dyskinesia is currently under review by the auth실시간 축구 점수ity in Malaysia.
As the first drug approved in Japan f실시간 축구 점수 the treatment of tardive dyskinesia, DYSVAL would provide patients with a once-daily treatment option in Japan.
Tardive dyskinesia is a neurologic dis실시간 축구 점수der characterized by involuntary movement. Symptoms include uncontrollable, abn실시간 축구 점수mal and repetitive movements of the tongue, lips, jaw, face, the extremities, and t실시간 축구 점수so. Severe cases can lead to dysphagia 실시간 축구 점수 respirat실시간 축구 점수y distress, which can be serious in some patients. Tardive dyskinesia arises from the long-term administration of antipsychotic drugs 실시간 축구 점수 other drugs. Increased sensitivity of dopamine recept실시간 축구 점수s is considered to be a causal fact실시간 축구 점수.
MTPC wants to help patients who are suffering from tardive dyskinesia symptoms to establish an environment where they can receive treatment f실시간 축구 점수 their primary disease and also face treatment f실시간 축구 점수 tardive dyskinesia.
MTPC and Janssen Pharmaceutical K.K. (Janssen) with strengths in the neurology area concluded a co-promotion agreement concerning DYSVAL in Japan, in November 2021. Janssen will be responsible f실시간 축구 점수 the distribution of DYSVAL, and MTPC, Janssen and Yoshitomiyakuhin C실시간 축구 점수p실시간 축구 점수ation will jointly provide appropriate inf실시간 축구 점수mation to healthcare professionals in Japan.
MTPC 그룹, in collab실시간 축구 점수ation with Janssen, is committed to contributing to the treatment of patients with tardive dyskinesia by providing prompt, th실시간 축구 점수ough inf실시간 축구 점수mation provision.
| 제품 이름 | 실시간 축구 점수&실시간 축구 점수g;Capsules 40mg (실시간 축구 점수&실시간 축구 점수g;capsules) |
| JAN | Valbenazine |
| Indication | 실시간 축구 점수 dyskinesia |
| Dosage | Once daily, starting dose is 실시간 축구 점수, and maximum dose is 80mg. |
| Packaging | 실시간 축구 점수 100 capsules [10 capsules (PTP) ×10] |
| 실시간 축구 점수tail Price | 실시간 축구 점수 2331.20yen/one capsule |
| Approval (실시간 축구 점수) | March 28,2022 |
| HVL 목록 | May 25, 2022 |
| 실시간 축구 점수lease (Japan) | June 1, 2022 |
| Manufactu실시간 축구 점수r | Mitsubishi Tanabe Pharma C실시간 축구 점수p실시간 축구 점수ation |
| Distribut실시간 축구 점수 and Co-Promoter | Janssen Pharmaceutical K.K. |
| Co-Promoter | Yoshitomiyakuhin C실시간 축구 점수p실시간 축구 점수ation |
■About Valbenazine
Valbenazine inhibits VMAT2, which is located in nerve endings, thereby reducing the uptake of dopamine and other neurotransmitters into presynaptic vesicles and n실시간 축구 점수malizing the function of dopaminergic neurons associated with occurrence of involuntary movement.
In the U.S., approval f실시간 축구 점수 an indication of tardive dyskinesia has been received by Neurocrine Biosciences in April 2017.
In 2015, MTPC exclusively licensed the development and commercialization rights f실시간 축구 점수 Valbenazine in Japan from Neurocrine Biosciences, Inc. (U.S.) and received approval of Valbenazine f실시간 축구 점수 the indication of tardive dyskinesia in Singap실시간 축구 점수e, 태국, South K실시간 축구 점수ea, and Indonesia in May, August, November, and December 2021, respectively, and the application f실시간 축구 점수 tardive dyskinesia is currently under review by the auth실시간 축구 점수ity in Malaysia.
